Anivia vs Kai'Sa ADC Matchup Guide | LaneStomp

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Anivia

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Kai'Sa

Anivia vs Kai'Sa

Confidence mediumUpdated Jun 7, 2026

Overview

The lane turns on Anivia punishing Kai'Sa's unsafe CS attempts due to her lower range and mobility.
Anivia wins extended trades and wave control, Kai'Sa needs isolated targets and support setup to threaten all-ins.
Anivia should keep the wave on her side to limit Kai'Sa's dash windows and force risky engages.

Trading pattern

Step forward to auto or use (Q)+(E) when Kai'Sa commits to last-hitting low-health caster minions without support peel.
Only punish last-hit approaches if enemy support cannot immediately trade back or zone you from brush.
Use (W) to block Kai'Sa's path and force her into your (Q) stun for reliable trades.

Danger windows

Kai'Sa is dangerous when her support applies CC enabling plasma stacks and she uses (R) to reposition for all-in.
Avoid stepping into brush or river zones controlled by enemy support that allow immediate follow-up on your trades.
Do not punish Kai'Sa's last hits if her (E) is available to dash away or if her support controls engage range.

Early game

Use early waves to thin minions and hold the wave near your turret to reduce Kai'Sa's dash safety.
Punish Kai'Sa when she steps up for caster minion last hits if her support is not threatening.
Avoid pushing hard early to deny Kai'Sa isolated (Q) damage and reduce her all-in potential with support.

Power spikes

After level 6 and first mana/AP item, Anivia can zone with (R) and farm safely, forcing Kai'Sa to play cautiously.
Kai'Sa's first completed item spike increases her all-in threat; respect her ability to commit with support setup.
Kai'Sa's level 6 (R) enables repositioning on plasma-marked targets; hold (Q) and (W) to punish her engage attempts.

Win conditions

Convert lane pressure by punishing Kai'Sa's unsafe CS attempts into health leads and forced recalls.
Use wave crashes near your turret to deny Kai'Sa plates and reset for your first item spike.
Leverage (R) zoning and scaling to control dragon area and teamfight positioning, limiting Kai'Sa's isolated target access.