Anivia vs Twitch ADC Matchup Guide | LaneStomp

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Anivia

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ADC

Twitch

Anivia vs Twitch

Confidence mediumUpdated Jun 7, 2026

Overview

This lane turns on punishing Twitch's last-hit attempts when his support can't immediately trade back.
Anivia wins extended trades with (R) zoning and (Q) stun setup, controlling wave priority through strong poke.
Twitch scales well post-6 but lacks early burst; use wave control to deny his stealth (Q) angles.

Trading pattern

Hit Twitch during last-hit animations with (Q) + (E) combo only if enemy support can't immediately punish.
Use (W) to block Twitch's path and force him into (Q) stun for safer trades.
Avoid trades if (Q) stealth or (W) slow is available to prevent his burst or chase potential.

Danger windows

Respect (Q) stealth window combined with enemy support follow-up for sudden all-ins.
Avoid standing near low-health minions when (R) is up to prevent multi-target poke.
Be cautious when Twitch has full poison stacks for (E) burst, especially if your flash is down.

Early game

Use first three waves to thin caster minions and hold wave near your tower to punish Twitch's low-health CS.
At level 2, punish Twitch stepping up for last hits with (Q) + auto if enemy support is out of zone.
Avoid pushing too hard early to reduce Twitch's stealth re-entry angles and limit his all-in windows.

Power spikes

After level 6 and first mana/AP item, Anivia can clear waves safely and zone Twitch with (R) for pick setups.
Twitch's level 6 (R) spike requires spacing to avoid grouped poke and prevents easy wave crashes.
Anivia's first item spike allows confident poke and wave control, forcing Twitch to play cautiously around cooldowns.

Win conditions

Convert wave control and last-hit punishment into item leads by forcing Twitch off the wave.
Use (R) zoning to deny Twitch turret plates and secure dragon vision with bot priority.
Scale into teamfights where Anivia's zone control and poke can safely output DPS while Twitch lacks safe flank angles.