Annie vs Qiyana MID Matchup Guide | LaneStomp

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Annie

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Mid

Qiyana

Annie vs Qiyana

Confidence mediumUpdated Jun 10, 2026

Overview

Use (R) to catch Qiyana off-guard and burst her before she can engage near terrain.
Deny Qiyana access to brush and walls to reduce her (R) threat and burst trades.
Prioritize farming safely and building passive stacks to enable reliable all-ins post-level 6.

Trading pattern

Punish Qiyana immediately after she uses (E) without lethal threat with (Q)+(W) burst and passive stun.
Avoid trading when Qiyana has the correct element active that empowers her (Q) poke and root.
Trade aggressively right after Qiyana expends (R) or (E) cooldowns to reduce her all-in threat.

Danger windows

(R) near terrain or river can stun and burst you if caught out of position.
Qiyana with the correct element active makes her (Q) root and poke highly threatening.
Pushing with (W) risks running out of mana and exposing yourself to Qiyana's all-in engages.

Early game

Focus on last hitting without pushing to avoid exposing yourself to (E) dash engage.
Use (E) shield proactively to absorb poke and mitigate Qiyana's short trades.
Avoid casting (W) to push the wave and conserve mana for burst trades or defensive shields.

Power spikes

Level 6 unlocks (R), giving Annie a strong pick tool to punish Qiyana near terrain or river.
First completed AP item significantly boosts Annie's burst damage and trade reliability.
Respect Qiyana's level 3 element setup and level 6 (R) spike that increase her burst potential.

Win conditions

Use (R) to catch Qiyana overextending or committing (E) without kill pressure.
Control brush and terrain access to limit Qiyana's burst and roaming potential.
Punish Qiyana's cooldowns with your (Q)+(W) burst combo to snowball lane control and pressure.