Ashe vs Vayne ADC Matchup Guide | LaneStomp

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Champion

Opponent

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Ashe

VS

ADC

Vayne

Ashe vs Vayne

Confidence mediumUpdated Jun 7, 2026

Overview

Ashe wins by punishing Vayne's short-range last-hit attempts with slows and poke.
Control wave near midline to limit Vayne's dash angles and force unsafe CS.
Ashe's lane pressure relies on range and slows; Vayne scales better in extended fights.

Trading pattern

Hit Vayne's auto during last-hit animations on melee or cannon minions if support threat is low.
Use (W) to slow Vayne before she can (Q) reposition, then follow with autos for extended poke.
Avoid punishes if enemy support controls brush or can immediately counter-engage after your step forward.

Danger windows

Vayne is most dangerous when (R) is active and (E) is available to pin you into terrain.
Avoid stepping forward when enemy support controls engage zones or brush near the wave.
Be cautious during Vayne's stealth (Q) reposition in (R); it enables her to dodge slows and re-engage.

Early game

Use first three waves to thin caster minions and keep wave just outside Vayne's auto range.
At level 2, punish Vayne's last hits when her (Q) is down and support can't trade back.
Position beside or slightly ahead of support to chain slows and deter Vayne's engage.

Power spikes

Level 6 unlocks (R) for long-range pick; use it with support follow-up to turn poke into kills.
First completed marksman item strengthens sustained slow pressure, enabling longer trades against Vayne.
Two-item power spike enhances kite potential; extend trades only when slows and peel keep Vayne at bay.

Win conditions

Convert slowed poke and (R) picks into health leads and force Vayne off cannon minions.
Crash waves after poke windows to take turret plates and secure dragon vision control.
Use lane priority and slows to set up picks before Vayne reaches two-item dueling power spike.