Cassiopeia vs Malzahar MID Matchup Guide | LaneStomp

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Cassiopeia

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Mid

Malzahar

Cassiopeia vs Malzahar

Confidence mediumUpdated Jun 10, 2026

Overview

Use (Q) to apply poison and force mid-range trades where you can extend with (E).
Deny Malzahar's push by killing Voidlings early to prevent him from gaining lane pressure.
Maintain spacing to avoid his (Q) silence and punish his predictable wave control pattern.

Trading pattern

Start trades by landing (Q) to poison, then chain (E) for sustained damage.
Use (W) to ground and slow if Malzahar tries to engage or escape.
Avoid trading when (W) is down or (Q) misses to prevent getting silenced or suppressed.

Danger windows

Malzahar's level 6 (R) suppression is a lethal all-in; avoid face-to-face fights without your (R).
Trading without poison or (W) exposes you to his silence and suppression combos.
Respect his passive Void Shift shield as it blocks your initial damage and poison application.

Early game

Focus on clearing Voidlings quickly to push Malzahar under tower and punish his early wave control.
Avoid extended trades without poison since his passive shield and silence can punish you.
Hold mid-range distance to dodge (Q) silence and prepare to counter his push attempts.

Power spikes

Level 6 (R) deters Malzahar from committing; use it to punish his ultimate channel or force resets.
First mana/AP item enhances your sustained damage and mana pool for longer trades.
Track Malzahar's level 6 (R) to avoid getting locked down and punish after it's used.

Win conditions

Win by landing (Q) to apply poison and forcing extended fights with repeated (E) damage.
Punish his predictable push by killing Voidlings and denying his lane pressure early.
Use (R) to interrupt his ultimate and secure kills when he faces you during all-ins.