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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Cassiopeia vs Vladimir MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Cassiopeia

VS

Mid

Vladimir

Cassiopeia vs Vladimir

Confidence mediumUpdated Jun 10, 2026

Overview

Use mid-range trades to apply poison and force extended fights where you out-DPS Vladimir.
Pressure Vladimir early to force his (W) defensively, limiting his healing and mobility.
Deny Vladimir free healing by punishing his short-range (Q) trades with sustained poke.

Trading pattern

Start trades by landing (Q) or (W) to poison, then follow with repeated (E) damage.
Use (W) to ground Vladimir's escape with (W) and keep him in your damage zone.
Avoid trades when Vladimir's empowered (Q) or (W) are available to prevent burst damage or escapes.

Danger windows

Vladimir's empowered (Q) enables strong short trades; avoid fighting during this.
His (R) burst is dangerous if you face him directly during cast.
(W) grants untargetability and slow; only punish after this cooldown expires.

Early game

Poke with (Q) and (W) to apply poison before Vladimir can safely use empowered (Q).
Avoid trading when Vladimir's empowered (Q) is ready; punish his cooldowns instead.
Maintain spacing to prevent Vladimir from healing freely with (Q).

Power spikes

Level 6 (R) greatly increases kill threat by punishing enemies facing you.
First mana/AP item boosts sustained damage and mana for longer trades.
Vladimir's level 6 (R) is a major burst threat; respect it in all-ins.

Win conditions

Win extended fights by maintaining poison stacks and out-DPSing with repeated (E).
Punish (W) cooldown by forcing trades or zoning him when he can't escape.
Use (R) in all-ins when Vladimir faces you to secure stuns and turn fights in your favor.

Tip: For Cassiopeia vs Vladimir, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup