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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Cassiopeia vs Zed MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Cassiopeia

VS

Mid

Zed

Cassiopeia vs Zed

Confidence mediumUpdated Jun 10, 2026

Overview

Control mid-range trades by landing (Q) to poison and force extended fights.
Use (W) to ground Zed's dashes and prevent his mobility advantage.
Avoid short burst trades and force Zed into sustained damage windows with (E).

Trading pattern

Initiate trades by landing (Q) or (W) to apply poison before committing.
Follow up with repeated (E) casts to maximize damage on poisoned targets.
Hold (W) to block Zed's mobility and avoid trades if (Q) misses or (W) is down.

Danger windows

(W)+(E)+(Q) combo is lethal; avoid trades when it's off cooldown.
His (R) all-in is deadly if you face him during the cast; respect this timing.
Avoid extended trades without (W) ready, as Zed can dash or escape easily.

Early game

Pressure Zed levels 1-3 to exploit his weak early all-in potential.
Punish missed (W) engages with immediate (Q) and extended (E) trades.
Conserve mana early to maintain (E) uptime for sustained damage after poisoning.

Power spikes

Level 6 (R) allows punishing Zed if he faces you during his all-in.
First mana/AP item boosts sustained damage, enabling more confident trades.
Respect Zed's level 3 (W)+(E)+(Q) combo as a strong all-in window to avoid.

Win conditions

Deny Zed free scaling by pressuring early and punishing missed (W) engages.
Use (W) to lock down his mobility and force extended fights where (E) excels.
Leverage level 6 (R) to stun or slow Zed during commits, securing kills or lane control.

Tip: For Cassiopeia vs Zed, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup