Dr. Mundo vs Pantheon TOP Matchup Guide | LaneStomp

Back to matchup selector

Champion

Opponent

RoleGenerate matchup

Dr. Mundo

VS

Top

Pantheon

Dr. Mundo vs Pantheon

Updated Jun 3, 2026

Overview

Dr. Mundo should focus on surviving Pantheon's early lane pressure and avoid extended trades until health scaling and (R) healing become effective.
Prioritize safe (Q) farming and use passive to block Pantheon's point-and-click stun to reduce his all-in threat.

Trading pattern

Trade only when (Q) lands consistently to slow Pantheon and when passive crowd control block is ready to negate his stun.
Avoid trading immediately after Pantheon uses (W) stun or while his (E) damage block is up to prevent losing burst trades.
Use (R) proactively before Pantheon's burst to sustain through damage and extend fights where Mundo's durability outmatches Pantheon.

Danger windows

Pantheon is most dangerous when his passive is stacked and (W) stun is available; avoid overextending or mispositioning during this time.
Be cautious when (E) damage block is up, as it negates your retaliation damage, making trades unfavorable.
After Pantheon hits level 6, watch for his (R) roam potential; hard push waves to punish his absence and avoid ganks.

Early game

Avoid engaging Pantheon before level 6 as his empowered (Q) and (W) stun create strong early burst trades.
Use (Q) to safely farm and maintain spacing, preventing Pantheon from stacking his passive for empowered trades.
Respect Pantheon's stun range and avoid taking trades when his (E) damage block is available to reduce return damage.

Power spikes

At level 6, activate (R) before Pantheon's burst to heal and chase, increasing survivability in fights.
After completing health-scaling items, pressure Pantheon by forcing longer trades that punish his weaker sustained damage.
Respect Pantheon's level 2-3 empowered (Q) and (W) combo; avoid trades during this window to prevent early health deficits.

Win conditions

Survive the early lane by farming safely with (Q) and passive crowd control block, then outlast Pantheon with superior healing and health scaling.
Use (R) to absorb burst damage and extend fights, forcing Pantheon to disengage or lose trades.
Pressure side waves after Pantheon roams with (R) to deny him map impact and secure your scaling advantage.