Garen vs Lissandra MID Matchup Guide | LaneStomp

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Champion

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Garen

VS

Mid

Lissandra

Garen vs Lissandra

Updated Jun 5, 2026

Overview

Expect a medium lane pressure matchup where you must manage short trades and passive health recovery against Lissandra's control and lockdown tools.
Focus on denying Lissandra free farm by using verified cooldown windows and wave states to force her off the wave.

Trading pattern

Initiate short trades by silencing with (Q), then spinning with (E), and disengage before Lissandra can retaliate with her root or engage combo.
Punish Lissandra when she uses (E) forward without follow-up by stepping in for quick trades before her escape.
Avoid committing if (Q) is baited or if Lissandra holds (W) ready, as she punishes melee commits heavily.

Danger windows

Respect (W) root and (R) stun combo when available, especially combined with jungle follow-up.
Avoid extended trades when your passive health regeneration is interrupted repeatedly, as it collapses your sustain.
Be cautious when Lissandra uses (E) to flank or engage, especially if you lack vision or allied support.

Early game

Use the first levels to hold a stable wave near your side and look for short (Q)+(E) trades when (W) root is on cooldown.
Avoid extended trades before level 6 as (W) and (R) can punish all-ins.
Punish Lissandra's CS attempts by stepping up immediately after she uses (Q) to farm or poke.

Power spikes

At level 6, use (R) execute pressure to finish off low-health Lissandra after chipping her with short trades.
After your first defensive or bruiser item, repeat controlled trades to absorb more damage and force Lissandra to respect your durability.
Respect Lissandra's level 6 (R) lockdown window; hold key defensive tools to survive her engage and punish once (R) is down.

Win conditions

Use short, durable trades around (Q) silence and (E) damage to chip Lissandra down and reach execute range for (R).
Deny Lissandra free farm by punishing her cooldowns and wave states to force her off the wave.
After level 6 and your first item, leverage your durability and execute to pressure side lanes and create kill opportunities through all-in windows.