K'Sante vs Vayne TOP Matchup Guide | LaneStomp

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Vayne

K'Sante vs Vayne

Updated Jun 3, 2026

Overview

Control the lane by managing (Q) stacks and using terrain to threaten displacement trades.
Prioritize denying Vayne safe scaling by avoiding long-range poke and forcing short trades near walls.
This is a control vs scale matchup where K'Sante must leverage front-line presence and terrain to isolate and punish Vayne.

Trading pattern

Trade around full (Q) stacks and (W) uptime, using (E) shield to mitigate burst and reposition.
Punish Vayne immediately after she uses (E) to knock back, as her engage threat is lower.
Avoid trading without (Q3) or (W) ready to prevent being outpaced by her true damage and mobility.

Danger windows

Vayne is most dangerous when (E) is ready to (E) you into terrain; respect spacing near walls.
After using (R), your durability drops; avoid all-ins until (W) and (Q3) are back.
Be cautious when (W) is down, as you lose key damage reduction and displacement tools.

Early game

Use (Q) to stack and engage in short trades when (W) is available to absorb Vayne's burst.
Avoid extended fights before level 6, focusing on controlled wave management and preserving (W) for key damage mitigation.
Position near terrain to limit Vayne's kiting space and punish her if she mispositions.

Power spikes

At level 6, use (R) only when you can isolate Vayne near terrain for a winning duel.
First tank item spike increases your durability, allowing safer trades and frontline control.
Respect Vayne's level 6 (R) stealth repositioning and (E) wall stun; avoid extended fights when these are up.

Win conditions

Use terrain to control space and isolate Vayne with (R) for decisive short trades.
Deny Vayne's scaling by forcing cooldowns and preventing safe farming through controlled aggression.
Frontline effectively in teamfights, peeling for carries and using displacement to protect allies and disrupt Vayne's positioning.