Kai'Sa vs Anivia ADC Matchup Guide | LaneStomp

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Kai'Sa

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Anivia

Kai'Sa vs Anivia

Confidence mediumUpdated Jun 7, 2026

Overview

Kai'Sa wins short trades after support CC enables plasma stacks and isolated (Q) damage.
Anivia controls wave with strong poke and zoning but lacks mobility, making her vulnerable to fast all-ins.
Kai'Sa benefits from thinned waves and support setup to punish Anivia's last-hit attempts safely.

Trading pattern

Step forward to auto or (W) poke when Anivia misses (Q) or uses (W) poorly, if support threat is low.
Avoid committing (E) forward before enemy engage or (Q) stun cooldown is spent to maintain safety.
Prioritize trades when Anivia is isolated from minions and plasma stacks are active for burst follow-up.

Danger windows

Avoid stepping up when (Q) stun and (R) slow are available, especially with enemy support in brush.
Beware of trades when enemy support can immediately follow or zone after Anivia lands (Q).
Do not commit (E) forward if enemy engage or crowd control is ready to punish Kai'Sa's reduced mobility.

Early game

Use the first three waves to farm safely and avoid stepping up before (Q) cooldown resets.
Punish Anivia's caster minion last hits only if enemy support cannot immediately trade back.
Keep wave small or thinned to maximize (Q) damage on Anivia instead of minions.

Power spikes

First completed item unlocks evolved abilities, allowing Kai'Sa to threaten safer all-ins and stronger poke.
Level 6 (R) enables repositioning onto marked targets, turning small support CC into lethal burst.
Respect Anivia's power spike after her first mana/AP item and level 6 when her poke and waveclear become harder to contest.

Win conditions

Convert isolated damage and plasma stacks into kills after first item and evolve thresholds.
Use health leads from last-hit punishments to crash waves, take plates, and force Anivia recalls.
Leverage bot priority and item spikes to secure dragon vision and teamfight positioning for backline access.