Karthus vs Zyra JUNGLE Matchup Guide | LaneStomp

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Champion

Opponent

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Karthus

VS

Jungle

Zyra

Karthus vs Zyra

Confidence mediumUpdated Jun 10, 2026

Overview

Prioritize full clears and avoid early river fights to protect your tempo against Zyra's poke and root threat.
Use your superior clear speed and scaling to outpace Zyra's jungle presence and influence.
Focus on tracking Zyra's movements to avoid early invades and set up safer objective control.

Jungle Plan

Cycle camps quickly to reach level 6 and first item spikes before engaging objectives.
Use vision to track Zyra's pathing and counter-jungle when she commits to river plants.
Prioritize dragon control after your first item to leverage your sustained objective damage and global (R) pressure.

Danger windows

Early levels when your clear health is low and Zyra's root can set up enemy follow-ups.
Isolated river fights where Zyra's plants and root can zone you out and leave you vulnerable.
Objective setups without vision control, as Zyra's zone control and knockup can punish face-checks.

Early game

Start full clear on your strong side and path away from river entrances where Zyra can contest.
Delay Scuttle crab fights until nearby lanes have priority to reduce counter-invade risk.
Avoid early river skirmishes unless your lanes can follow up on Zyra's immobility and lack of reliable gank threat.

Power spikes

Level 6 unlocks (R), allowing you to impact fights globally and finish low-health enemies after skirmishes.
First AP item significantly boosts your clear speed and objective damage, increasing map pressure.
Full clear resets provide tempo windows to invade or secure vision before Zyra can react.

Win conditions

Convert fast full clears and item spikes into sustained objective damage and vision control.
Use (R) to finish off low-health enemies after your team initiates or skirmishes start.
Deny Zyra jungle tempo by counter-jungling camps when she overextends planting seeds or controlling brush.