Kayle vs Vayne TOP Matchup Guide | LaneStomp

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Vayne

Kayle vs Vayne

Updated Jun 3, 2026

Overview

Prioritize surviving early levels without deaths to reach your ranged form and item breakpoints safely.
Avoid giving Vayne a passive lane to freely scale by managing wave position and using (Q) and (W) to sustain through pressure.
This is a scale vs scale matchup where Kayle must endure early pressure to become a late-game DPS threat with invulnerability timing.

Trading pattern

Use (Q) to slow and reduce Vayne's resistances, then back off before she can engage with (E).
Only commit to longer trades when you have reached ranged form and (R) is available to negate burst.
Punish (E) cooldown by stepping forward for short trades when it's down and she cannot (E) you into terrain.

Danger windows

You are vulnerable before level 6 when Vayne's early pressure and (E) wall stun can secure kills.
When your (R) is down, Vayne's burst and (E) engage become more reliable; avoid extended trades.
Be cautious if the wave is frozen far from your tower, as Vayne can punish your poor positioning and lack of escape.

Early game

Play defensively and farm safely, using (W) to heal and (Q) to slow Vayne's engage attempts.
Avoid extended trades before level 6 when you lack ranged attacks and (R) invulnerability.
Keep the wave near your tower to reduce Vayne's ability to all-in or freeze the lane away from you.

Power spikes

At level 6, use your ranged form and (R) to stabilize lane and deny Vayne's all-in attempts.
Respect Vayne's level 6 (R) stealth repositioning and avoid fights when she can outplay with stealth tumbles.
Your late-game DPS and invulnerability timing make you a major side-lane and teamfight threat; protect uptime and fight front-to-back.

Win conditions

Survive early levels by farming safely and using (Q) and (W) to mitigate Vayne's pressure.
Reach level 6 and item thresholds to unlock ranged trades and (R) invulnerability for safer fights.
In late game, leverage your ranged DPS and (R) timing to dominate side-lane duels and front-to-back teamfights, avoiding early all-ins and freezes.