Kog'Maw vs Vayne ADC Matchup Guide | LaneStomp

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Champion

Opponent

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Kog'Maw

VS

ADC

Vayne

Kog'Maw vs Vayne

Confidence mediumUpdated Jun 7, 2026

Overview

This lane turns on (W) uptime to win extended trades and punish Vayne's short-range CS attempts.
Kog'Maw needs to keep wave states stable near his side to avoid Vayne's dash and (E) angles.
Vayne's early agency and mobility force Kog'Maw to rely on support peel and (W) range windows to contest farm.

Trading pattern

Trade only during (W) uptime to extend range and DPS, hitting Vayne when she commits to last hits.
Step forward for autos or (Q) poke when (Q) is down and enemy support cannot counter-engage.
Give up punish windows if enemy support controls brush or threatens immediate follow-up trades.

Danger windows

Avoid trading when (W) is down, as Kog'Maw loses range and DPS, making him vulnerable to Vayne's burst.
Respect (E) cooldown and wall angles; stepping near terrain without peel invites stuns and all-ins.
Beware of enemy support positioning in brush or river; their engage can quickly punish Kog'Maw's immobility.

Early game

Use the first three waves to hold the wave near your turret to limit Vayne's dash angles.
Punish Vayne's last hits on low-health caster minions when (W) is active and support can peel.
Avoid pushing early without vision to prevent (E) wall stun setups and aggressive trades.

Power spikes

(W) active: Enables Kog'Maw's real lane range and DPS window; contest CS and trades aggressively.
First on-hit item: Turns extended fights into tank-shred windows; group with peel and force objectives.
Two on-hit items: Front-to-back fights heavily favor Kog'Maw; position safely to maximize DPS output.

Win conditions

Survive early lane by farming safely and punishing Vayne's short-range CS attempts during (W) uptime.
Convert health leads and wave control into turret plate damage and dragon vision control.
Scale into two-item spikes with peel support, enabling dominant front-to-back teamfights where Kog'Maw can shred targets safely.