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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Lissandra vs Neeko MID Matchup Guide | LaneStomp

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Champion

Opponent

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Lissandra

VS

Mid

Neeko

Lissandra vs Neeko

Updated May 31, 2026

Overview

Lissandra is a control mage who must manage Neeko's disguise and E root threat by controlling engage range.
Prioritize denying Neeko safe all-in windows and avoid extended poke trades to maintain lane pressure.

Trading pattern

Trade when Neeko commits into W root range or after she misses E, using Q poke and W lockdown.
Use E plus R only when allies can follow up to lock down Neeko or punish her disguise.
Avoid forcing fights if R is unavailable or if Neeko is positioned behind minions to block E.

Danger windows

Neeko's E through minions and R ultimate create dangerous all-in windows; avoid close-range without R.
Lissandra is vulnerable if she uses E forward without follow-up or if R is down.
Punish Neeko when she misses E or uses R defensively, reducing her threat.

Early game

Use Q to farm safely and poke while holding W to punish Neeko's close-range commits.
Respect Neeko's E root angles through minions and avoid engaging without R or jungle follow-up.
Maintain medium lane pressure by controlling wave and denying Neeko easy E setups.

Power spikes

Level 6 R is Lissandra's major spike for lockdown and self-peel.
First completed AP or utility item enhances Lissandra's control and damage.
Respect Neeko's level 6 Neeko R for burst and knock-up threat.

Win conditions

Control short-range trades with W root and punish Neeko's missed E with lockdown and burst.
Use E and R to create flank engages or self-peel, enabling jungle or team follow-up.
Deny Neeko calm scaling by forcing cooldowns and maintaining wave pressure to limit her disguise and all-in setups.

Tip: For Lissandra vs Neeko, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated May 31, 2026New matchup