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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Lissandra vs Zilean MID Matchup Guide | LaneStomp

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Champion

Opponent

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Lissandra

VS

Mid

Zilean

Lissandra vs Zilean

Confidence mediumUpdated Jun 10, 2026

Overview

Use (Q) to farm and poke while holding (W) to punish Zilean's close approach.
Avoid extended trades before level 6 when Zilean's double bomb stun and (R) threaten.
Look for flanks with (E) and reliable follow-up to lock down Zilean or his ADC.

Trading pattern

Use (Q) to poke and control wave, punish Zilean if he mispositions for bombs.
Hold (W) to root Zilean when he steps up to place bombs or engage.
Only commit (E) plus (R) engage when you have ally follow-up or a guaranteed lockdown.

Danger windows

Respect Zilean's double bomb stun setup, especially around level 2 and 3.
Avoid fighting when (R) revive is available to prevent wasted burst.
Watch for his (E) speed boosts enabling kiting or disengage, limiting your engage.

Early game

Track Zilean's level 2 to avoid his double bomb plus speed trade window.
Thin the wave early to reduce bomb zone control and force Zilean to reposition.
Avoid overextending without (R) ready to counter his revive and stun combo.

Power spikes

Level 6 (R) unlocks your lockdown and self-peel, enabling safer all-ins or roams.
First completed AP or utility item boosts your trade reliability and wave pressure.
Post-(R) cooldown, Zilean is vulnerable to aggressive trades and forced resets.

Win conditions

Use (R) to lock down Zilean or his ADC for kills or forced summoners.
Create flank angles with (E) to surprise and chain CC with (W) and (R).
Deny Zilean's bomb zones by wave management and punish cooldowns to gain lane priority.

Tip: For Lissandra vs Zilean, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 10, 2026New matchup