Naafiri vs Lissandra MID Matchup Guide | LaneStomp

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Naafiri

VS

Mid

Lissandra

Naafiri vs Lissandra

Updated May 31, 2026

Overview

Naafiri aims to chip Lissandra with Q poke before committing to all-ins with W and R-enhanced chase.
Apply medium lane pressure to prevent Lissandra from safely setting up her engage and lockdown tools.

Trading pattern

Start trades by landing Q to apply bleed, then commit with W and E only if Lissandra's W root and R stun are on cooldown.
Exploit windows when Lissandra uses E forward without safe recast by punishing her with your pack-enhanced R chase.
Avoid all-ins if Q poke has missed or if Lissandra's crowd control is ready to interrupt your W dash.

Danger windows

Lissandra is most dangerous when her W root and R stun are up, ready to punish your W engage.
Avoid committing W into her crowd control or when her E flank path is unpredictable.
Be cautious if Lissandra has jungle assistance to follow up on her lockdown abilities.

Early game

Use Q to poke and create bleed stacks early, forcing Lissandra to respect your damage before she can engage.
Avoid committing W when Lissandra's W root or R stun is available to prevent getting locked down.
Keep the wave positioned to avoid predictable W engages and to maintain escape paths from Lissandra's E flank.

Power spikes

Level 6 R empowers your chase and burst, increasing kill pressure on isolated or low-health Lissandra.
First lethality item spike makes your Q poke and burst significantly more threatening.
Respect Lissandra's level 6 R for her lockdown and self-peel potential, which can turn fights against you.

Win conditions

Win by consistently landing Q poke to lower Lissandra's health, then using R to isolate and burst her down.
Punish Lissandra's cooldowns, especially her E and R, by timing your W engage when her crowd control is unavailable.
Control wave state to keep escape routes open and deny Lissandra safe setups for her engage and lockdown combos.