Nasus must focus on safe farming and stacking (Q) while respecting Akali's early lane pressure and high mobility.
This is a scaling juggernaut versus a mid-game assassin matchup where Nasus avoids early all-ins and aims for extended fights after reaching key power spikes.
Trading pattern
Trade only when you have (W) ready to punish Akali if she commits too close or overextends.
Avoid fighting inside (W) shroud zone; wait for it to expire before engaging.
Use your stacked (Q) damage and (R) durability to win extended trades once you have enough stacks and level 6.
Danger windows
Be cautious when (W) is up as it grants her safe trading and escape; avoid extended fights during this.
Before you reach meaningful (Q) stacks and level 6, Akali's high mobility and burst make you vulnerable to all-ins.
Avoid freezing the wave far from your tower to prevent Akali and her jungler from coordinating dives.
Early game
Prioritize last-hitting with (Q) near your tower to avoid Akali's poke and all-in potential.
Avoid engaging before level 6 when (W) and (E) combo can punish you hard.
Use (W) defensively to slow Akali if she overextends without her (W) available.
Power spikes
At level 6, use (R) to survive Akali's burst and force extended fights where your stacks and (W) slow shine.
Akali's level 3 unlock of (Q)-(W)-(E) combo requires you to respect her all-in threat and avoid early trades.
Once you have high (Q) stacks and a defensive item, pressure side lanes to force Akali to respond or lose objectives.
Win conditions
Survive early lane pressure by farming safely and stacking (Q) near your tower.
After level 6 and with sufficient (Q) stacks, use (W) and (R) to punish Akali's overextensions in side lanes.
Force extended duels where your scaling damage and durability outmatch Akali's burst and mobility.
Tip: For Nasus vs Akali, read overview, trading pattern, and danger windows first for a fast Top lane check.