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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Qiyana vs Cassiopeia MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Qiyana

VS

Mid

Cassiopeia

Qiyana vs Cassiopeia

Updated May 31, 2026

Overview

Qiyana must use terrain and element control to burst Cassiopeia before she can extend trades with poison and E.
Pressure Cassiopeia early to deny her extended DPS and scaling potential by forcing short trades and punishing cooldowns.

Trading pattern

Prepare the correct element with W and use Q for poke or root to start trades before committing with E.
Punish Cassiopeia when Cassiopeia W is down to dash in safely and burst.
Avoid committing E without lethal threat or escape path, especially if Cassiopeia is poisoned and ready to trade back with E damage.

Danger windows

Respect Cassiopeia R stun when facing her during all-ins near terrain.
Avoid trading when Cassiopeia W is up as it grounds your dash and slows you.
Be cautious when Cassiopeia has poison applied and can chain E damage and healing.

Early game

Use level 3 power spike to set an element and threaten quick burst trades before Cassiopeia can apply poison.
Avoid prolonged fights where Cassiopeia can repeatedly cast E and sustain with poison.
Control brush and river terrain to maximize R threat and roam opportunities after wave control.

Power spikes

Level 3 unlocks full Q-W-E combo for burst trades.
Level 6 R is a major terrain-based all-in threat.
First lethality item significantly increases burst potential to punish Cassiopeia's low mobility.

Win conditions

Use element swaps and terrain to create lethal burst trades before Cassiopeia can sustain.
Snowball river and flank fights leveraging R's terrain stun to secure kills.
Deny Cassiopeia extended fights by punishing cooldowns and forcing short burst trades.

Tip: For Qiyana vs Cassiopeia, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated May 31, 2026New matchup