Qiyana vs Lissandra MID Matchup Guide | LaneStomp

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Champion

Opponent

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Qiyana

VS

Mid

Lissandra

Qiyana vs Lissandra

Updated May 31, 2026

Overview

Qiyana must manage element choice and terrain to threaten burst trades and control river skirmishes against Lissandra.
Pressure the lane moderately to deny Lissandra easy setups and avoid letting her scale passively.

Trading pattern

Prepare the correct element with W, use Q to poke or root, and only commit E when Lissandra's W and R are down or she is near terrain.
Punish Lissandra if she uses Lissandra E aggressively without safe recast by engaging with E and burst.
Avoid trading away from terrain where R impact is minimal and Lissandra can retaliate safely.

Danger windows

Respect Lissandra's Lissandra W root and Lissandra R stun especially near her turret or terrain.
Avoid all-ins when R is down or fight is away from terrain.
Be cautious if Lissandra's Lissandra E is ready for engage or flank angles with jungle follow-up.

Early game

Use level 3 power spike to set up element combos and short burst trades before Lissandra can safely engage.
Avoid committing E without lethal threat or escape path to prevent Lissandra punishing with W root.
Maintain brush or river access to maximize element and R threat for early skirmishes.

Power spikes

Level 3 unlocks Q-W-E combos and first burst trade potential.
Level 6 R greatly increases kill threat near terrain and river.
First lethality item completion amplifies burst damage to punish Lissandra's cooldowns.

Win conditions

Use element swaps and terrain to burst Lissandra after she uses key cooldowns.
Snowball river skirmishes and flank fights with R to secure kills and roam pressure.
Deny Lissandra safe wave control to prevent her from setting up reliable engages with Lissandra E and Lissandra R.