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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Ryze vs Lissandra MID Matchup Guide | LaneStomp

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Champion

Opponent

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Ryze

VS

Mid

Lissandra

Ryze vs Lissandra

Updated May 31, 2026

Overview

Ryze wants a controlled lane to farm safely and use waveclear to create roam opportunities.
Avoid giving Lissandra free all-in windows by respecting her W root and R lockdown potential.

Trading pattern

Use E and Q to poke and spread damage, holding W to root Lissandra if she commits.
Punish Lissandra when her E is on cooldown or she mispositions her engage path.
Avoid trading when Lissandra's W or R are available as she can lock you down quickly.

Danger windows

When Lissandra's W and R are up, avoid stepping into her root range or committing without backup.
Be cautious if Lissandra has jungle support to follow up on her engage with E and R.
Low mana or W cooldown on Ryze reduces his ability to punish Lissandra's engages, increasing danger.

Early game

Focus on farming safely and using E and Q for short trades without stepping into Lissandra W range.
Avoid extended trades if low on mana or if Lissandra's R is available.
Track Lissandra's E usage to punish her engage attempts when it's down or poorly positioned.

Power spikes

Ryze's first mana/AP item significantly boosts his rotation damage and sustain.
Level 6 R enables impactful map plays but does not increase lane burst.
Respect Lissandra's level 6 Lissandra R for lockdown or self-peel, which increases her all-in threat.

Win conditions

Scale safely through farming and use spell rotations to chip Lissandra when she overextends.
Use waveclear to control the lane and create opportunities for R roams.
Punish Lissandra's cooldowns on E and R by stepping up for trades or forcing her to miss farm.

Tip: For Ryze vs Lissandra, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated May 31, 2026New matchup