Sylas vs Cassiopeia MID Matchup Guide | LaneStomp

Back to matchup selector

Champion

Opponent

RoleGenerate matchup

Sylas

VS

Mid

Cassiopeia

Sylas vs Cassiopeia

Updated May 31, 2026

Overview

Sylas is a high-mobility skirmisher who must use E to engage and W to sustain through Cassiopeia's poke.
Pressure Cassiopeia early to deny her mid-range sustained trades and prevent her from comfortably applying poison and extending fights.

Trading pattern

Engage with E to close distance quickly and trade with W heal and Q slow, then disengage before Cassiopeia can stack E damage.
Punish Cassiopeia when she misses Q or W by committing to extended trades using your sustain and mobility.
Avoid trading when Cassiopeia's W is available to ground your E and when her R is ready and you are facing her.

Danger windows

Respect Cassiopeia's R stun window, especially when facing her directly during engages.
Avoid engaging when Sylas's E or W is on cooldown, as Cassiopeia's sustained damage and crowd control can punish you hard.
Be cautious when pushed under turret, as Cassiopeia's poke and waveclear can punish Sylas's melee range.

Early game

Use E to dodge Cassiopeia Q and W, then engage short trades with W heal and autos before backing off.
Avoid prolonged trades early if Cassiopeia has poison applied and W is up, as her sustained E damage punishes melee range.
Prioritize level 3 to unlock full Q-W-E combo for stronger skirmishes before Cassiopeia scales.

Power spikes

Sylas's level 3 unlocks full Q-W-E combo for strong trades and sustain.
Sylas's level 6 R can turn fights if Cassiopeia's ultimate is valuable.
Cassiopeia's level 6 Cassiopeia R is a major threat that punishes facing her during all-ins.

Win conditions

Use E to engage or threaten and force Cassiopeia into uncomfortable short trades where you can out-sustain with W.
Capitalize on missed Cassiopeia Q or W to force extended fights and snowball lane pressure.
Steal and use Cassiopeia's R if possible to turn all-ins in your favor and deny her stun threat.