Syndra vs Lissandra MID Matchup Guide | LaneStomp

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Syndra

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Mid

Lissandra

Syndra vs Lissandra

Updated May 31, 2026

Overview

Syndra is a medium pressure burst mage who must use Q and W to control space and avoid giving Lissandra easy engage angles.
Focus on denying Lissandra safe short-range trades to prevent her from setting up her W root and R lockdown.

Trading pattern

Poke with Q and W to build sphere setup, then punish Lissandra's close commits with E stun into burst.
Respect Lissandra W root and R lockdown by holding E for disengage and counter-engage.
Avoid trading when E is on cooldown or if Lissandra's R is available to lock you down.

Danger windows

When E (E) is down, Syndra is vulnerable to Lissandra's engage and crowd control.
Lissandra's R can stun or self-peel, creating dangerous windows for Syndra if caught out.
Be cautious if Lissandra uses E aggressively without follow-up, as she may retreat and punish missed spells.

Early game

Use Q and W to poke and keep Lissandra at bay before level 6 when her engage threat rises.
Avoid committing if E (E) is down to prevent being punished by Lissandra's crowd control and burst.
Watch for Lissandra's E engage attempts and punish if she overextends without follow-up.

Power spikes

Syndra's level 6 R is a major burst spike to threaten all-ins.
Syndra's first completed mage item increases poke and burst potential.
Respect Lissandra's level 6 R for lockdown and her first AP item for increased control and damage.

Win conditions

Control space with Q and W to zone Lissandra and force her to miss engages.
Look for E stuns on sphere setups to burst Lissandra before she can use her R defensively.
Deny Lissandra scaling by punishing her cooldowns and maintaining lane pressure to reach mid-late game power spikes safely.