Syndra vs Sett MID Matchup Guide | LaneStomp

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Syndra

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Mid

Sett

Syndra vs Sett

Updated Jun 3, 2026

Overview

Syndra is a medium lane pressure burst mage who must control space with spheres and punish Sett's melee approach using (E) stun into (R) burst.
Manage lane control to deny Sett the close-range brawls he wants and avoid giving him free grit stacks.
This is a control-versus-brawling matchup where Syndra must leverage ranged poke and crowd control to prevent Sett from engaging effectively.

Trading pattern

Poke with (Q) and (W) to chip Sett and hold (E) to punish his (E) pull or any overcommit.
Avoid missing (E) as it is Syndra's only reliable disengage and crowd control against Sett's melee all-ins.
After Sett uses (W) shield or misses (E), step forward to apply more pressure and threaten burst combos.

Danger windows

Respect (E) stun and pull, which can lock Syndra down if caught near minions or spheres.
Beware (W) shield and true damage when grit stacks are high; avoid extended trades in these windows.
After level 6, (R) can reposition Syndra into dangerous fights; maintain spacing and avoid predictable positioning.

Early game

Use (Q) and (W) to poke Sett early and keep him at melee range to prevent grit buildup.
Avoid extended trades before level 6 when (R) and grit shield are not yet threatening.
Position spheres carefully to maintain (E) stun threat and punish Sett's attempts to close distance near minions.

Power spikes

At level 6, (R) enables strong all-ins; use it to punish Sett's commitment or force defensive resets.
Syndra's first completed mage item strengthens poke and trade reliability; increase wave pressure and poke frequency after this.
Syndra's upgraded (Q) and levels 11/16 improve poke cooldown and damage; use these to contest space and punish loose Sett positioning.

Win conditions

Use (Q) and (W) to control space and poke Sett out of melee range, denying him grit buildup.
Look for (E) stuns into (R) burst combos to punish Sett's melee engages or cooldown mistakes.
Maintain wave pressure and cooldown awareness to force Sett into unfavorable trades or miss farm, securing lane control and scaling advantage.