Trundle excels at early dueling and objective control, so prioritize contesting river and camps where you can trap Kha'Zix with (E).
Use your strong invade resistance to challenge Kha'Zix's isolation-dependent playstyle by forcing fights near lanes with priority.
Manage the map by leveraging your sustained damage and stat steal to deny Kha'Zix scaling through counter-jungling and objective control.
Jungle Plan
Full clear toward river Scuttle, contest it only when your lanes have priority to avoid Kha'Zix's isolation picks.
Invade and counter-jungle after tracking Kha'Zix's path, focusing on trapping him with (E) near narrow jungle exits or objectives.
Use vision control around dragon and Rift Herald to force Kha'Zix into grouped fights where your dueling and sustain outmatch his isolation burst.
Danger windows
Be cautious contesting Scuttle or jungle camps alone early, as Kha'Zix can exploit isolation with (Q) and (R) stealth for burst.
Avoid low-health clears or forced smite fights without lane priority since Kha'Zix's mobility and reset on (E) can punish mistakes.
Isolated river fights or objective setups without vision control are risky due to Kha'Zix's ability to enter from fog and pick off targets.
Early game
Start with a clear path that leads you toward the first river Scuttle to contest it aggressively if nearby lanes have priority.
Avoid isolated fights early where Kha'Zix can use fog and stealth to burst you; instead, path through camps near your lanes to set up pillar traps.
Use your (W) zone to sustain through clears and prepare for early skirmishes around objectives, but back off if Kha'Zix is missing and lanes can't assist.
Power spikes
Level 6 unlocks (R), allowing you to drain health and resistances from tanks or bruisers, making extended duels favorable; use it on high-value targets before committing.
First dueling item completion strengthens your ability to force side-lane fights and pressure towers, punishing Kha'Zix's weaker extended fight potential.
Kha'Zix's level 6 (R) and first damage item spike increase his pick threat; respect fog and avoid isolated fights during these windows.
Win conditions
Convert early dueling advantage into securing dragon and Rift Herald by controlling vision and forcing grouped fights.
Use (E) pillar to trap Kha'Zix during counter-jungling or objective fights, denying his escape and pick potential.
Leverage your (R) stat steal on durable targets to win extended skirmishes and pressure side lanes, denying Kha'Zix scaling and forcing his team into unfavorable fights.
Tip: For Trundle vs Kha'Zix, read overview, trading pattern, and danger windows first for a fast Jungle lane check.