Twitch vs Zeri ADC Matchup Guide | LaneStomp

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Twitch

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ADC

Zeri

Twitch vs Zeri

Confidence highUpdated Jun 7, 2026

Overview

Twitch wins by punishing Zeri's predictable CS paths with stealth ambushes and poison stacks.
Twitch struggles in early short trades but outscales Zeri through stealth and item spikes.
Control wave near your side to create stealth angles and reduce Zeri's dash escape options.

Trading pattern

Step forward to auto and apply (W) poison when Zeri commits to last hits, only if enemy support can't punish.
Avoid punishing if enemy support controls brush or can engage immediately after your step forward.
Use (Q) stealth to reposition unseen and open trades when Zeri overextends for CS without wall escape nearby.

Danger windows

Respect (E) dash cooldown; she is vulnerable to all-ins or poke when it's down.
Avoid fighting near walls when (R) is active, as Zeri's extended fight and mobility increase danger.
Do not punish last hits if enemy support can immediately follow or zone after your step forward.

Early game

Use the first three waves to farm safely and avoid early trades before level 6.
Watch Zeri's last-hit animations on caster minions to punish with autos and (W) slow if support threat is low.
Hold wave near your tower to deny Zeri easy wall (W) poke angles and reduce her dash safety.

Power spikes

Level 6 (R) gives Twitch long-range piercing trades; open from stealth to hit Zeri and support lined with minions.
First completed marksman item improves Twitch's all-in threat and poison burst damage; punish Zeri's extended trades.
Two-item stealth spike enables Twitch to flank and delete targets; use vision denial to create unseen angles against Zeri's mobility.

Win conditions

Convert stealth ambushes into health leads and crash waves to take turret plates and force recalls.
Use lane priority and vision denial to set up dragon control and grouped fights where (R) pierces multiple targets.
Scale safely through early lane, then leverage Twitch's superior late-game DPS and stealth to outplay Zeri in teamfights.