Vayne vs Aphelios ADC Matchup Guide | LaneStomp

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Vayne

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Aphelios

Vayne vs Aphelios

Confidence mediumUpdated Jun 7, 2026

Overview

This lane turns on Vayne punishing Aphelios's last-hit attempts when he steps up without support threat.
Vayne wins extended trades and side-lane duels by using (Q) repositioning and (E) wall stuns against Aphelios's immobility.
Aphelios controls poke windows with weapon cycling, so Vayne must manage wave state to deny his free poke and scale safely.

Trading pattern

Step forward to auto-attack Aphelios when he commits to last-hitting low-health minions if his support is not in engage range.
Use (Q) to reposition and punish Aphelios's lack of dash, especially when his Gravitum root is on cooldown.
Hold (E) to (E) Aphelios into bot lane walls or terrain for a stun, creating all-in windows or escapes.

Danger windows

Respect Aphelios's Calibrum poke when he has ammo and support is ready to zone or engage.
Avoid stepping into range during Gravitum root windows combined with enemy support follow-up.
Beware Infernum splash and (R) burst during grouped minion waves or close-range fights where Aphelios can output heavy damage.

Early game

Use the first three waves to hold a slow push near your side, denying Aphelios easy Calibrum poke.
Punish Aphelios during caster minion last hits if enemy support cannot immediately trade back.
Avoid pushing without vision to prevent ganks or support engage exploiting your low waveclear.

Power spikes

Level 6 (R) lets Vayne stealth (Q) and outplay Aphelios's limited mobility; use it to dodge root and reposition.
First marksman item spike increases Vayne's dueling and wave-clear, enabling safer punishes on Aphelios's weapon cooldowns.
Two-item spike empowers true damage DPS, allowing Vayne to pressure side lanes and punish Aphelios's immobility with vision control.

Win conditions

Convert last-hit punishments into health leads and crash waves to take turret plates and force Aphelios recalls.
Use side-lane pressure after two-item spike to force Aphelios into unfavorable fights or split vision control.
Scale into late-game true damage DPS and use (E) stuns to isolate Aphelios in teamfights, maximizing your impact while kiting.