Vayne vs Kog'Maw ADC Matchup Guide | LaneStomp

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Vayne

VS

ADC

Kog'Maw

Vayne vs Kog'Maw

Confidence mediumUpdated Jun 7, 2026

Overview

Vayne wins short trades by punishing Kog'Maw's immobility and lack of dash with (Q) autos.
Kog'Maw controls extended trades during (W) uptime, so Vayne must exploit downtime to deny farm.
The lane decides on last-hit punish windows and wave states that allow Vayne to kite freely.

Trading pattern

Step forward to auto Kog'Maw during his last-hit animations when (W) is down and support threat is low.
Hold (E) for wall stuns to punish Kog'Maw if he overextends or walks near terrain.
Use (Q) to reposition and dodge poke, never (Q) forward into his engage or support range.

Danger windows

Respect (W) uptime combined with enemy support peel, as his DPS and poke range spike.
Avoid stepping into brush or river zones without vision, where Kog'Maw's support can engage or zone you.
Be cautious when (E) is down, as your engage threat and peel potential drop significantly.

Early game

Use the first three waves to hold a thin wave near your tower to limit Kog'Maw's poke range.
Punish Kog'Maw's last hits with (Q) autos only if enemy support cannot immediately trade back.
Avoid pushing without vision to prevent ganks and losing control over engage angles near walls.

Power spikes

Level 6 (R) gives Vayne stealth on (Q), enabling safer all-ins and outplays against Kog'Maw's lack of mobility.
First marksman item spike improves Vayne's ability to contest CS and punish Kog'Maw's forced farm windows.
Two-item spike turns Vayne into a strong side-lane duelist, pressuring Kog'Maw who relies on peel and protection.

Win conditions

Convert last-hit punishments into health leads to force Kog'Maw off the wave and deny plates.
Crash waves after punishing to set up dragon control and force Kog'Maw recalls before item spikes.
Scale into side-lane duels post two-item spike, using (R) stealth and (E) wall stuns to outplay in extended fights.