Vayne vs Nilah ADC Matchup Guide | LaneStomp

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Vayne

VS

ADC

Nilah

Vayne vs Nilah

Confidence mediumUpdated Jun 7, 2026

Overview

Vayne wins by punishing Nilah's short-range CS attempts with (Q) autos and holding (E) for wall stuns.
Control wave near your side to deny Nilah safe all-ins and force her into risky last-hit positions.

Trading pattern

Step forward to auto Nilah during her last-hit animation if enemy support is out of position.
Use (Q) to reposition and punish Nilah when her (W) anti-auto is down.
Hold (E) to (E) Nilah into walls when she tries to engage or dash forward with (E).

Danger windows

Respect (W) window when it blocks your autos, as she can all-in safely during this.
Avoid trading when Nilah's support controls brush or can immediately follow your punish.
Be cautious when (R) is up and support is ready to engage, as they can force committed fights.

Early game

Use the first three waves to hold a freeze near your tower, forcing Nilah to walk into your auto range.
Punish Nilah's last hits on low-health caster minions only if enemy support cannot immediately trade back.
Avoid pushing early without vision to prevent Nilah's support from enabling her engage with (E).

Power spikes

Level 6 (R) empowers your stealth repositioning and dueling; use it to outplay Nilah's all-ins.
First marksman item spike improves your damage and allows safer punishment of Nilah's short-range trades.
Two-item spike turns you into a strong side-lane duelist, pressuring Nilah who struggles to match your true damage.

Win conditions

Convert last-hit punishments into CS leads and crash waves to deny Nilah farm and plates.
Use your superior scaling and (R) stealth to pressure side lanes and force Nilah under tower.
Leverage lane priority to secure dragon vision and safe teamfight positioning for your late-game DPS role.