Vex vs Annie MID Matchup Guide | LaneStomp

Vex vs Annie MID Matchup Guide | LaneStomp

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Champion

Opponent

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Read Overview → Trading Pattern → Danger Windows first for the fastest Mid lane plan.

Vex into Anniemedium

Overview

Use your passive Doom fear to interrupt Annie's burst trades and control lane tempo.
Pressure Annie's mana by forcing her to push waves with early.
Prioritize punishing Annie's cooldowns and avoid extended trades without fear ready.

Trading pattern

Initiate trades using your passive fear to quickly proc electrocute.
Punish Annie after she wastes or passive stun by engaging with and slow.
Respect Annie's + burst when her passive stun is stacked; avoid trading then.

Danger windows

Avoid all-ins when your is down due to lack of mobility and reset.
Respect Annie's passive stun at 4 stacks and availability as high-threat windows.
Punish Annie's low mana windows after forcing her to push waves with .

Early game

Use and passive fear to trade before Annie stacks her stun.
Force Annie to push with to drain her mana and open all-in windows.
Avoid trading when your fear is baited or on cooldown to prevent Annie's burst combo.

Power spikes

At level 6, your enables strong engages and resets; use it for verified all-ins.
Your first completed AP burst item increases trade reliability; pressure waves and trades confidently.
Respect Annie's level 6 and first AP item spike as lethal burst windows.

Win conditions

Use your passive fear to control trades and proc electrocute efficiently for lane dominance.
Deny Annie farm and picks by pressuring her mana and forcing wave control.
Use resets to all-in after Annie expends key cooldowns or misses her stun timing.

Tactical tip

For Vex vs Annie, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 27, 2026