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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Vex vs Cassiopeia MID Matchup Guide | LaneStomp

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Champion

Opponent

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Vex

VS

Mid

Cassiopeia

Vex vs Cassiopeia

Updated Jun 1, 2026

Overview

Vex is a high lane pressure burst mage who must use her passive fear to control Cassiopeia's limited mobility.
Deny Cassiopeia the chance to establish extended trades where she can stack poison and use repeated E damage.

Trading pattern

Initiate trades by landing fear to proc electrocute and burst before Cassiopeia can respond.
Punish Cassiopeia when her Cassiopeia Q or Cassiopeia W is down to prevent poison application.
Use W shield to absorb Cassiopeia's poke and follow up with E slow to control her movement.

Danger windows

Cassiopeia's Cassiopeia W grounds your dashes; avoid committing when it's available.
Cassiopeia R is dangerous if you face her directly during her all-in window.
If you fail to land fear or your R is down, you become vulnerable to Cassiopeia's sustained damage.

Early game

Use passive fear to force Cassiopeia out of range before she can land Q or W poison.
Avoid extended trades to prevent Cassiopeia from applying poison and healing with E.
Pressure early levels to limit Cassiopeia's ability to hold space and scale safely.

Power spikes

Level 6 R is your main engage and reset tool; use it to punish Cassiopeia's immobility.
Your first completed AP burst item significantly increases kill pressure.
Respect Cassiopeia's level 6 R which can stun if you face her during all-ins.

Win conditions

Use your passive fear to win short trades and prevent Cassiopeia from applying poison.
All-in with R after baiting Cassiopeia's Cassiopeia W or when Cassiopeia R is down.
Deny Cassiopeia extended fights to stop her from stacking poison and healing with E.

Tip: For Vex vs Cassiopeia, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 1, 2026New matchup