Vladimir vs Cassiopeia MID Matchup Guide | LaneStomp

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Vladimir

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Mid

Cassiopeia

Vladimir vs Cassiopeia

Updated Jun 1, 2026

Overview

Vladimir should focus on surviving Cassiopeia's mid-range poke and avoid early forced fights to reach his scaling power spikes.
Maintain a low-pressure lane state to farm safely and use Q sustain to outlast Cassiopeia's poke.

Trading pattern

Take short trades when empowered Q is ready, but avoid trading when Cassiopeia has poison stacks and can follow up with repeated E.
Save W to avoid Cassiopeia R or W damage rather than using it for minor trades.
Punish Cassiopeia when she misses Q or uses W defensively, as her immediate trade threat drops and her mobility is less restricted.

Danger windows

Be cautious when Cassiopeia's R is ready and you are forced to face her directly during trades or all-ins.
Avoid engaging when your W is down, as you lose your untargetability and become vulnerable to Cassiopeia's sustained damage.
Cassiopeia's W grounding zone creates a danger window where your mobility and escape options are limited.

Early game

Use Q to sustain through Cassiopeia's poke and avoid extended trades where her E damage and poison stack up.
Avoid engaging when Cassiopeia's W is available as it grounds and slows, limiting your ability to reposition.
Play around Cassiopeia's medium early agency by farming safely and not overcommitting to trades before level 6.

Power spikes

Respect Cassiopeia's level 6 R which can stun or slow if you face her during all-ins.
Vladimir's major spikes are level 6 R and first completed AP item, which increase his burst and teamfight presence.
Cassiopeia's first mana/AP item also strengthens her sustained damage, so avoid extended trades after she completes it.

Win conditions

Survive early lane by using Q sustain and avoiding Cassiopeia's poison and extended E trades.
Scale into mid-game power spikes with R and AP items to threaten grouped fights and burst damage.
Use empowered Q and W cooldown windows to punish Cassiopeia's reduced threat and force favorable trades.