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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Zed vs Cassiopeia MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Zed

VS

Mid

Cassiopeia

Zed vs Cassiopeia

Updated Jun 1, 2026

Overview

Zed is a high-mobility assassin aiming to burst Cassiopeia before she can apply sustained poison damage.
Use lane pressure to deny Cassiopeia a calm mid-range zone and prevent her from scaling comfortably.

Trading pattern

Use W + E for guaranteed damage and follow up with Q poke before committing to all-in with R.
Punish Cassiopeia when she misses Cassiopeia Q or wastes Cassiopeia W by aggressively engaging.
Avoid fighting inside Cassiopeia W zone to prevent being grounded and slowed during trades.

Danger windows

Cassiopeia's Cassiopeia R is dangerous when you are forced to face her during all-ins.
Missing your W engage or shadow combo leaves you vulnerable to Cassiopeia's sustained damage.
Avoid extended fights when Cassiopeia has Cassiopeia W up to prevent being trapped or slowed.

Early game

Avoid extended trades before level 3 when Zed's combo is not fully unlocked and Cassiopeia can punish.
Use early wave control to force Cassiopeia to farm under pressure and limit her ability to land Cassiopeia Q or W.
Respect Cassiopeia W's grounding effect by not engaging recklessly without your W ready.

Power spikes

Zed's level 3 unlocks W-E-Q combo for strong poke and all-in potential.
Zed's level 6 R allows lethal burst if Cassiopeia is caught out.
Cassiopeia's level 6 Cassiopeia R greatly increases her all-in threat and must be respected.

Win conditions

Use your mobility and burst to kill Cassiopeia before she can stack poison and sustain damage.
Punish Cassiopeia's missed Cassiopeia Q and Cassiopeia W cooldowns with quick all-ins.
Deny Cassiopeia the space to apply poison and force her out of lane to prevent her scaling.

Tip: For Zed vs Cassiopeia, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 1, 2026New matchup