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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Zoe vs Cassiopeia MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Zoe

VS

Mid

Cassiopeia

Zoe vs Cassiopeia

Updated Jun 1, 2026

Overview

Zoe is a poke mage who must pressure Cassiopeia early to deny her mid-range sustained trades and scaling.
Use high lane pressure and early agency to force Cassiopeia into passive farming rather than extended fights.

Trading pattern

Initiate trades by landing E to enable burst with Q and R follow-up.
Punish Cassiopeia immediately after she misses Cassiopeia Q or when Cassiopeia W is down to avoid her slowing and grounding effects.
Avoid extended trades where Cassiopeia can repeatedly cast Cassiopeia E on poisoned targets.

Danger windows

Be cautious when Zoe's E is missed or on cooldown, as burst threat drops and Cassiopeia can punish.
Respect Cassiopeia W's grounding effect which can trap Zoe if used poorly.
Avoid facing Cassiopeia directly during her R window to prevent stun or slows.

Early game

Fish for E to set up burst trades before Cassiopeia can apply poison and extend fights.
Avoid committing when E is on cooldown to prevent being punished by Cassiopeia's sustained damage.
Use R + Q to poke safely from unexpected angles and keep Cassiopeia at range.

Power spikes

Zoe's level 6 R unlocks extended poke angles and burst potential.
Zoe's first completed AP burst item significantly increases kill threat.
Respect Cassiopeia's level 6 Cassiopeia R which punishes enemies facing her during all-ins.

Win conditions

Win by landing E reliably to burst Cassiopeia before she can apply poison and extend trades.
Use R + Q to poke from unexpected angles, denying Cassiopeia safe farming and scaling.
Punish Cassiopeia's cooldowns on Cassiopeia Q, Cassiopeia W, and Cassiopeia R to maintain lane dominance and snowball advantage.

Tip: For Zoe vs Cassiopeia, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 1, 2026New matchup