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Overview

Role Plan

Danger Windows

Early Game

Power Spikes

Win Conditions

Zoe vs Lissandra MID Matchup Guide | LaneStomp

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Champion

Opponent

RoleGenerate matchup

Zoe

VS

Mid

Lissandra

Zoe vs Lissandra

Updated Jun 1, 2026

Overview

Zoe is a poke mage with high early agency and lane pressure aiming to control the lane by landing E for burst combos.
Pressure Lissandra early to deny her safe scaling and force her to play behind her cooldowns.

Trading pattern

Initiate trades by landing E sleep, then use Q and R to maximize burst damage from unexpected angles.
Respect Lissandra W root and R stun cooldowns; avoid trading when these are available.
Punish Lissandra when she uses E forward without safe recast or when R is down by stepping forward aggressively.

Danger windows

Be cautious when Lissandra's R is available as it can lock you down or self-peel effectively.
Avoid overextending if Lissandra's W root is off cooldown and she has allies nearby.
Punish Lissandra after she uses E forward and cannot safely recast or when R is down.

Early game

Use E to fish for sleep and follow up with Q and R for extended poke before Lissandra can engage.
Avoid committing if E misses, as Zoe becomes vulnerable to Lissandra's W root and R lockdown.
Maintain distance to prevent Lissandra from engaging with E and W without follow-up.

Power spikes

Zoe's level 6 R unlocks extended poke angles and burst potential.
Zoe's first completed AP burst item significantly increases kill pressure.
Lissandra's level 6 R is a major threat; respect its availability to avoid lockdown.

Win conditions

Win by landing reliable E sleeps and bursting with Q and R from unexpected angles.
Deny Lissandra a calm scaling lane by constant poke and forcing her to miss farm or use cooldowns defensively.
Use superior range and mobility to avoid her engage and pressure her under turret or during cooldowns.

Tip: For Zoe vs Lissandra, read overview, trading pattern, and danger windows first for a fast Mid lane check.

Updated Jun 1, 2026New matchup