Zyra vs Senna SUPPORT Matchup Guide | LaneStomp

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Zyra

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Support

Senna

Zyra vs Senna

Confidence mediumUpdated Jun 9, 2026

Overview

Control brush with plants to deny Senna and her ADC safe positioning and poke angles.
Use (E) root to create ADC follow-up windows and punish Senna stepping up for souls.
Hold (R) for enemy engage or grouped fights to turn their engage into a zone control scenario.

Trading pattern

Start trades from brush with (Q) and threaten (E) root to set up ADC follow-up.
Hold (R) to punish Senna's engage or root attempts, turning fights into your plant zone advantage.
Avoid missing (E) root; losing root control weakens your poke and exposes your ADC to Senna's counter-engage.

Danger windows

(W) root combined with her ADC's follow-up creates high threat windows; stay behind plants.
Enemy engage cooldowns up with brush control lost increases vulnerability; avoid standing in hook range.
Senna stepping up for soul collection can bait your (E); punish only when ADC can follow immediately.

Early game

Win level 2 by landing (E) root plus plant poke, enabling your ADC to follow up safely.
Seed brush early to force Senna and her ADC through plant zones, limiting their poke angles.
Avoid overpushing when your ADC wants to freeze; maintain brush control and lane priority for safe trades.

Power spikes

Level 2: Root plus plant poke opens strong trade windows; coordinate with ADC for follow-up.
Level 3: Full kit unlocks stronger brush control and poke, increasing your zone dominance.
Level 6: (R) enables turning enemy engages into favorable zone fights; use with ADC follow-up and river vision.

Win conditions

Convert brush and root control into denied enemy ADC positioning and safe ADC access.
Use (R) with ADC follow-up to dominate clustered fights and secure dragon or lane objectives.
Set river vision and time roams after wave crashes to pressure mid and maintain lane control.